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OBJECTIVE@#Accumulation of estrogenic compounds and other carcinogens in normal breast tissues contributes to unpredictable breast cancer incidence during adolescence and throughout life. To assess the role of parabens in this phenomenon, the paraben content of adjacent normal-malignant breast tissues is measured in women with breast cancer living in Isfahan Province, Iran.@*METHODS@#Adjacent normal-malignant breast tissue samples were obtained from 53 subjects. The parabens including methyl-paraben (MePB), ethyl-paraben (EtPB), propyl-paraben (PrPB), and butylparaben (BuPB) were extracted from the sample supernatant and then subjected to gas chromatography analysis.@*RESULTS@#Some risk factors for breast cancer were stimulated by parabens in adjacent malignant-normal breast tissues among young and middle-aged women with breast cancer. We observed a significant association for dose-response pattern of MePB [OR = 98.34 (11.43-185.2), P = 0.027] for both ER+ and PR+ women and MePB [OR = 164.3 (CI: 112.3-216.3), P < 0.001] for HER2+ women than women with negative receptors. The risk of 95-fold increase in MePB dose and 164-fold increase in ΣPBs dose were significant for women with hereditary breast cancer in first-degree relatives.@*CONCLUSION@#These results may promote future epidemiology studies and strategies to improve women's lifestyle and consume paraben-free products.
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Introduction: In recent times, one of the most important purposes of sustainable development has been defined as the protection of environmental health. Using appropriate and innovative infrastructures such as nanotechnology is a solution to walk along the path of sustainable development and solves many environmental problems. The purpose of this study is to review the application of carbon nanotubes in the removal of environmental pollutants, based on conducted studies
Materials and Methods: All scientific data related to the issue were collected from scientific databases of Google Scholar, Scopus, Elsevier, and SID to evaluate and conduct the study. Keywords such as carbon nanotubes, environmental pollutant, sustainable development, and environmental health were used. 85 articles were also used in this review research [1993-2016]
Results: Based on the evaluated studies, the results indicated that common methods of sewage treatment are not enough to remove the mentioned environmental pollutants completely. In the mentioned methods, despite high decomposition, the amount of mineralization has been reduced and the toxicity of wastewaters has remained unchanged or has increased. Adsorption has been propounded due to its simplicity and lower energy consumption compared with other methods. Carbon nanotubes [CNTs] are unique one-dimensional macromolecules which have high thermal resistance and chemical stability. Adsorption through CNT as the adsorbent in the treatment of drinking water and sewage polluted with pharmaceutical, petroleum, heavy metal, and leachate pollutants has been studied widely
Conclusion: This study indicated CNT as effective adsorbents that have high potential to protect the environment and promote sustainable development
Subject(s)
Environmental Pollution , Nanotechnology , Wastewater , Adsorption , Sewage , Review Literature as TopicABSTRACT
Introduction: Arsenic is known as a carcinogenic compound in drinking water . It can cause acute and chronic effects on human health. In this study, the effect of polyamidoamine dendrimer generation 3 [PAMAM G3] as adsorbents for removal of arsenic [V].From aqueous solutions was evaluated
Methods: Adsorption experiment was studied in batch system and the effect of different variables like pH, contact time, concentrations of arsenic and adsorbent dosage on adsorption was studied. Therefore, absorption kinetics and equilibrium isotherms were determined
Results: The results showed that adsorption process is affected by some parameters such as initial concentration, adsorbent and contact time
The three models of isotherm included Langmuir, Freundlich and Dubinin- Radeshkuvich were studied that Freundlich and Langmuir isotherms were more compliant with results
Conclusion: According to results, can be concluded that adsorption with dendrimer is an appropriate method with high efficiency for removal arsenic from aqueous solutions
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Air pollution is a hazardous environmental problem with several adverse health effects including its impact on the development of chronic diseases as diabetes mellitus. This study aimed to investigate the association of geographical distribution of air quality index [AQI] and type 2 diabetes mellitus in an air-polluted city by using geographic information system [GIS]. This cross-sectional study was conducted in Isfahan, Iran. The records that have been registered from 2009 to 2012 in major referral public diabetes clinics were gathered; they included data of 1467 diabetic patients. Their living area was represented with spots in the city map. AQI data were also interpolated from monitoring stations spreading around the city. The GIS maps of air pollutants and diabetes were developed and the associations were determined. The density of diabetic population was higher in highly polluted areas compared with areas with the lower levels of air pollution. No significant correlation was documented between the distribution of diabetic patients and air pollution level throughout the city. Although the density of diabetic patients was higher in areas with higher air pollution, but the lack of association between AQI and the prevalence of diabetes might be because the air of different parts of the city was highly polluted, and we could not compare the prevalence of diabetes in areas with clean and polluted air
Subject(s)
Humans , Male , Female , Air Pollution , Geographic Information SystemsABSTRACT
The aim of this study is to investigate the association of calcium and magnesium concentration of drinking water with cardiovascular disease [CVDs] in urban and rural areas of a city in Iran. This case-control study was conducted in 2012 in Khansar County in Isfahan province, Iran. We used the official data of the Provincial health center regarding the chemical analysis data of urban and rural areas including the hardness, calcisum and magnesium content of drinking water. Data of patients hospitalized for CVD in the only specialty hospital of the city was gatheresd for the years of 2010 and 2011. In 2010, the increase in the calcium hardness above 72 mg/L, the prevalence of CVDs in 1000 population decreased; in 2011 this decrease in CVDs was observed for calcium hardness of more than 75 mg/L. In 2010, the level of Mg hardness in water ranged from 23 to 57 mg/L. By increasing Mg hardness level above 31 mg/L in 2010 and above 26 mg/L in 2011, the number of CVD in 1000 people decrease. Our study suggests favorable protective effects of water hardness, mainly water magnesium content, on CVDs. Water hardness, as well as calcium and magnesium content of drinking water may have a protective role against CVDs. Further experimental studies are necessary to determine the underlying mechanisms and longitudinal studies are required to study the clinical impacts of the current findings
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In this research, an experimental study to evaluate nutrient removal from synthetic wastewater by a lab-scale moving bed biofilm process was investigated. Also, kinetic analysis of the process with regard to phosphorus and nitrogen removal was studied with different mathematical models. For nutrient removal, the moving bed biofilm process was applied in series with anaerobic, anoxic and aerobic units in four separate reactors that were operated continuously at different loading rates of phosphorus and nitrogen and different hydraulic retention times. Under optimum conditions, almost complete nitrification with an average ammonium removal efficiency of 99.72% occurred in the aerobic reactor. In the aerobic reactor, the average specific nitrification rate was 1.92 g NOx-N [NOx-N=NO2-N +NO3-N] produced/kg volatile suspended solids. hour [VSS.h]. Denitrification rate increased with increasing NOx-N loading in the second anoxic reactor. The aerobic phosphate removal rate showed good correlation with the anaerobic phosphate release rate. Under optimum conditions, the average total nitrogen and phosphorus removal efficiencies were 80.9% and 95.8%, respectively. As a result of the moving bed biofilm process [MBBR] kinetic analysis, the Stover-Kincannon model was chosen for modeling studies and experimental data analysis. The Stover-Kincannon model gave high correlation coefficients for phosphorus and nitrogen removal, which were 0.9862 and 0.986, respectively. Therefore, this model could be used in predicting the behavior or design of the moving bed biofilm process